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Piper nigrum
95% Piperine
Piper nigrum seed extract
94-62-2, 84929-41-9
Feed - Pet Food
Bioavailability, Vector

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Bioperine® - The most studies of the natural nutrients enhancer from Piperine

Piperine is an alkaloid from black pepper (Piper nigrum) giving it that pungent taste. It is produced using exclusively ethanol, including the oleoresinic part (undoubtedly the only currently rich in piperine extract).
Used before 1997, Bioperine (95-98% piperine) is black pepper (Piper nigrum) extract, well-documented and patented for its action to boost absorption of nutrients (different tests and studies have been conducted many times, including beta carotene and so other carotenoids, CoQ10, Resveratrol, Minerals such as Iron, Selenium, .... liposoluble vitamins, curcuminoids, etc ...).
Bioperine was declared not novel foods in March 2011 by the Belgium authorities. As an activity of "nutrient enhancer," it is not subject to the EFSA authorizations since improving bioavailability may not be a claim (the claims are linked to the nutrient itself). It is produced using only ethanol, including the oleoresinic part (undoubtedly the only currently-rich extract piperine). Its use is oral, 5mg per dose, and patented - including Europe (use of piperine as a gastrointestinal absorbation enhancer).
Its counterpart for topical use is Cosmoperine (tetra hydropiperin, so hydrogenation) extract from piper nigrum as well.
Number of internal - by Sabinsa - and external studies have shown that the safety of Bioperine - and the history of its use (millions of doses already consumed) - is one of the best evidence. The controversial studies sometimes highlighted were carried out at doses up to 1000 times higher than those recommended.
Many in-vivo studies are available, last one on the bioavailability of Iron, especially in sport nutrition.
5 mg per dose 3 times a day. It can be used for feed as well.

Using Bioperine, you use the reference, and get the studies, name and history of uses.
Sabinsa Corporation specifically discovered that this 95% purified extract of an important alkaloid from black pepper can enhance the bioavailability of many nutrients with virtually no loss to them in the body.

Black pepper - Historical spice and medicine

Black pepper (Piper nigrum, Piperaceae) has been used in human diet from ancient times and is one of the most widely used spices throughout the world. It has also been used in various traditional medicines, preservatives and health supplements.
The Materia Medica of Ayurveda, documents black pepper as one of the three herbs essential for several prescriptions and formulations.
Piperine, one of our principal black pepper extracts, corresponds to the alkaloid responsible for the pungency of black pepper and long pepper. It has been used in some forms of traditional medicine. The usual dose of 5mg correspond to ... a well peppered foodstuff.

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